Most stable option to play ISO on PSP 3000?


I have read several sticky posts and still don't understand a lot of things so I'm going to ask directly. What is the most stable and safest option to play ISO on a PSP 3000? Currently I have OFW 6.39 and a 4GB Sandisk memory stick. Any help is appreciated. If anyone can point me to a guide that would be even better.
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