| Achievement | How to unlock |
|---|
| Blood Bank (100 points) | Spill 1000 litres of blood. |
| Chained (10 points) | Perform your first combo. |
| Circus Act (50 points) | Kill 50 Splatts with the Cannon. |
| Complex Equations (20 points) | Achieve a X4 combo. |
| Doctor Jones (50 points) | Flatten 50 Splatts with a Boulder. |
| Final Descent (10 points) | Complete all Bio Zone Laboratories. |
| First Blood (10 points) | Kill your first Splatt. |
| First Draft Complete (10 points) | Complete all Basement Laboratories. |
| Freeze (10 points) | Kill a Splatt whilst it's stunned. |
| Frying Tonight (50 points) | 50 Splatts killed in a Lava Pit. |
| Full Data (10 points) | Complete all Graduate and Master Objectives in a laboratory. |
| Half Way There (50 points) | Discover 50 WTDs. |
| Hoarder (100 points) | Amass 100 Stars. |
| In the Book (10 points) | Discover your first WTD. |
| Inconceivable (100 points) | Earn three stars in all Laboratories in every zone. |
| Killer Research (10 points) | Complete all Sector Zero Laboratories. |
| Killing 101 (10 points) | Claim your first 101 kills. |
| Moving Desks (10 points) | Complete all Control Room Laboratories. |
| Nailed to the Wall (50 points) | 100 Splatts impaled on Spikes. |
| One Book Closes (10 points) | Complete all Laboratories. |
| Orientation (10 points) | Complete the Training Laboratories. |
| Page Turner (10 points) | Discover 10 WTDs. |
| Pencil Chewer (10 points) | Complete a Basement Laboratory. |
| Reorder Body Bags (50 points) | Claim your first 50 victims. |
| Rest In Pieces (100 points) | Discover All 101 WTDs. |
| Splatter-cide (100 points) | Claim your first 1000 kills. |
| Splattunfuder's Pet (10 points) | Achieve a three star rating for all Laboratories in any zone. |
| Star Studded (10 points) | Achieve your first three star rating. |
| Stuffed Splatt (10 points) | 10 Cakes completely consumed. |
| We All Die Together (10 points) | Kill a Tank, Alpha and Rapid within one second. |
